EC Number |
Natural Substrates |
---|
1.6.3.1 | more |
direct interaction of TLR4 with NAD(P)H oxidase 4 isozyme is essential for lipopolysaccharide-induced production of reactive oxygen species and activation of NF-kappaB |
1.6.3.1 | more |
the production of reactive oxygen species is initiated by the phygocyte NADPH oxidase |
1.6.3.1 | more |
enzyme isoform Nox3 plays an integral role in insulin-induced p42/44 MAPK signal transmission and VEGF-A production |
1.6.3.1 | more |
enzyme provides hydrogen peroxide for iodine metabolism in the thyroid |
1.6.3.1 | more |
enzyme-derived reactive oxigen species modulate cerebral vascular tone under physiological conditions |
1.6.3.1 | more |
essential role of enzyme-generated reactive oxigen species in insulin-stimulated activation of hypoxia-inducible factor 1 |
1.6.3.1 | more |
formation of a complex consisting of enzyme, guanine exchange factor for Rac, betaPix, and enzyme organizer NoxO1 is a critical step in EGF-induced generation of reactive oxygen species |
1.6.3.1 | more |
plasma membrane NADPH oxidase participates in the Ni-induced production of reactive oxygen species, and Ca2+ may be involved in the oxidative stress induced by nickel in wheat roots |
1.6.3.1 | more |
reactive oxygen species generated by the transverse tubule NADPH oxidase enzyme activate via redox modification the neighboring RyR1 Ca2+ release channels |
1.6.3.1 | more |
active NAD(P)H oxidase is required for vascular endothelial growth factor activation of phosphoinositide 3-kinase-Akt-forkhead, and p38 mitogen-activated kinase, but not extracellular signal-related kinase 1/2 or c-Jnu N-terminal kinase. The permissive role of NADPH oxidase on phosphoinositide 3-kinase-Akt-forkhead signaling is mediated at post-vascular endothelial growth factor receptor levels and involves the nonreceptor tyrosine kinase Src |