EC Number |
Natural Substrates |
---|
1.5.1.27 | 1,2-Dehydroreticuline + NADPH |
formation of the precursor of morphinan alkaloids |
1.5.1.27 | 1,2-Dehydroreticuline + NADPH |
the enzyme catalyzes the provision of (R)-reticuline for the formation of morphinian alkaloids that possess also (R)-configuration at the chiral centre |
1.5.1.27 | 1,2-dehydroreticulinium + NADPH + H+ |
- |
1.5.1.27 | more |
the bifunctional CYP82Y2 fusion enzyme termed reticuline epimerase (PsREPI) is a fusion between a cytochrome P450 (CYP) and an aldo-keto reductase (AKR) catalyzes the S-to-R epimerization of reticuline via 1,2-dehydroreticuline |