EC Number   |
Natural Substrates |
|---|
    1.4.1.1 | DL-alanine + H2O + NAD+ |
- |
| 1.4.1.1 | glycine + H2O + NAD+ |
- |
| 1.4.1.1 | glyoxylate + NH3 + NADH + H+ |
- |
| 1.4.1.1 | L-Ala + H2O + NAD+ |
- |
| 1.4.1.1 | L-Ala + H2O + NAD+ |
the physiological role is to catabolize L-Ala to pyruvate and NH3, inducible by L-Ala, D-Ala and 11 other D-amino acids. The enzyme catabolizes L-Ala, and thereby limits the amount of L-Ala available to alanine racemase for the synthesis of D-Ala |
| 1.4.1.1 | L-Ala + H2O + NAD+ |
since the physiological environment of the organism has a neutral pH, it can be assumed that the enzyme catalyzes exclusively the formation of L-Ala |
| 1.4.1.1 | L-Ala + H2O + NAD+ |
enzyme is involved in primary ammonium assimilation and the rapid formation of key metabolites pyruvate and NH3 from L-Ala and also in cell differentiation |
| 1.4.1.1 | L-Ala + H2O + NAD+ |
enzyme is required for utilization of alanine as a sole nitrogen source, enzyme is required for optimal growth under anaerobic conditions |
| 1.4.1.1 | L-Ala + H2O + NAD+ |
physiological role in nitrogen metabolism in Streptomycetes |
| 1.4.1.1 | L-Ala + H2O + NAD+ |
role in NH3 assimilation and alanine catabolism |
