EC Number   |
Natural Substrates |
|---|
   1.14.13.82 | 4-hydroxy-3-methylbenzoate + O2 + NADH + H+ |
- |
| 1.14.13.82 | isovanillic acid + NAD(P)H + H+ + O2 |
O-demethylation by IvaAB |
| 1.14.13.82 | m-anisate + O2 + NADH + H+ |
- |
| 1.14.13.82 | more |
the enzyme forms a vanillate demethylase complex of VanA, a terminal oxygenase subunit, with VanB, a ferredoxin-like subunit, performing demethylation of vanillic acid and veratric acid |
| 1.14.13.82 | syringate + NADH + H+ + O2 |
- |
| 1.14.13.82 | vanillate + O2 + NAD(P)H + H+ |
- |
| 1.14.13.82 | vanillate + O2 + NADH + H+ |
- |
| 1.14.13.82 | vanillate + O2 + NADH + H+ |
able to demethylate one methoxy group or to monohydroxylate one methyl group in the meta position |
| 1.14.13.82 | vanillate + O2 + NADH + H+ |
i.e. protocatechiuc acid |
| 1.14.13.82 | vanillic acid + NAD(P)H + H+ + O2 |
functional coupling between vanillate-O-demethylase and formaldehyde detoxification pathway, formaldehyde is further converted to formate by glutathione-dependent formaldehyde dehydrogenase, encoded by gene frmA |
