EC Number   |
Natural Substrates |
|---|
   1.14.13.39 | 2 L-arginine + 3 NADPH + 3 H+ + 4 O2 |
- |
| 1.14.13.39 | 2 L-arginine + 3 NADPH + 3 H+ + 4 O2 |
NO from acetylsalicylic acid-activated enzyme is involved in thrombolysis, overview |
| 1.14.13.39 | 2 L-arginine + 3 NADPH + 3 H+ + 4 O2 |
NO is an important signalling molecule, released by numerous cells, that acts in many tissues to regulate a diverse range of physiological and biological processes, including neurotransmission, immune defence and the regulation of apoptosis. NO plays a major role in the killing of intracellular pathogens as part of the innate immune response |
| 1.14.13.39 | 2 L-arginine + 3 NADPH + 3 H+ + 4 O2 |
overall reaction, overview |
| 1.14.13.39 | 2 L-arginine + 3 NADPH + 3 H+ + 4 O2 |
regulatory mechanism, overview |
| 1.14.13.39 | 2 L-arginine + 3 NADPH + 3 H+ + 4 O2 |
overall reaction |
| 1.14.13.39 | 2 L-arginine + 3 NADPH + 3 H+ + 4 O2 |
endothelial nitric oxide synthase (eNOS) is responsible for maintaining systemic blood pressure, vascular remodeling and angiogenesis |
| 1.14.13.39 | 2 L-arginine + 3 NADPH + 3 H+ + 4 O2 |
the enzyme plays an important role in host defense system by catalyzing the production of nitric oxide |
| 1.14.13.39 | 2 L-arginine + 3 NADPH + 4 O2 + 3 H+ |
- |
| 1.14.13.39 | 2 L-arginine + 3 NADPH + 4 O2 + 3 H+ |
physiological functions and pathophysiology of the isoforms |
