EC Number   |
Natural Substrates |
|---|
    1.14.13.2 | 4-hydroxybenzoate + NADPH + H+ + O2 |
- |
| 1.14.13.2 | 4-hydroxybenzoate + NADPH + H+ + O2 |
4-hydroxybenzoate degradation proceeds via hdroxylation to 3,4-dihydroxybenzoic acid and then conversion to catechol, which is cleaved to cis,cis-muconic acid through ortho-catechol cleavage |
| 1.14.13.2 | 4-hydroxybenzoate + NADPH + O2 |
- |
| 1.14.13.2 | 4-hydroxybenzoate + NADPH + O2 |
enzyme is induced by 4-hydroxybenzoate |
| 1.14.13.2 | 4-hydroxybenzoate + NADPH + O2 |
the enzyme prefers NADPH to NADH. 4HBA hydroxylase can be induced by 4HBA, 4-cresol, and 4-hydroxybenzaldehyde |
| 1.14.13.2 | 4-hydroxybenzoate + NADPH + O2 |
inducible enzyme |
| 1.14.13.2 | 4-hydroxybenzoate + NADPH + O2 |
first step in the bacterial metabolism when 4-hydroxybenzoate is used as growth substrate |
| 1.14.13.2 | 4-hydroxybenzoate + NADPH + O2 |
enzyme of the toluene-4-monooxygenase catabolic pathway |
| 1.14.13.2 | 4-hydroxybenzoate + NADPH + O2 |
enzyme catalyzes an intermediate step in the degradation of aromatic compounds in soil microorganisms |
| 1.14.13.2 | 4-hydroxybenzoate + NADPH + O2 |
high degree of homology observed between the enzyme from Comamonas and of Pseudomonas and Acinetobacter indicates the common evolutionary origin of the enzyme in the divergent pathways of 4-hydroxybenzoate among these soil bacteria of different genera |
