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Results 1 - 8 of 8
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EC Number Natural Substrates Commentary (Nat. Sub.)
Display the reaction diagram Show all sequences 1.1.1.422(+)-(1S,2S)-pseudoephedrine + NAD+ -
Display the reaction diagram Show all sequences 1.1.1.422(1S,2S)-(+)-pseudoephedrine + NAD+ -
Display the reaction diagram Show all sequences 1.1.1.422(S,R)-(+)-ephedrine + NAD+ -
Display the reaction diagram Show all sequences 1.1.1.422(S,S)-(+)-pseudoephedrine + NAD+ -
Display the reaction diagram Show all sequences 1.1.1.4221-phenylpropan-1,2-dione + NAD+ -
Display the reaction diagram Show all sequences 1.1.1.4221-phenylpropan-1,2-dione + NAD+ PseDH overcomes the stability of the conjugated molecule PPD by reducing it to alpha-hydroxyketone (S)-PAC. Phenylacetylcarbinol (PAC) cannot be oxidized by these dehydrogenases and possibly undergoes a cleavage reaction to yield benzaldehyde and acetaldehyde
Display the reaction diagram Show all sequences 1.1.1.4221-phenylpropan-1,2-dione + NADH + H+ -
Display the reaction diagram Show all sequences 1.1.1.422more PseDH is strictly stereospecific for the other diastereomers, (S,S)-(+)-pseudoephedrine and (S,R)-(+)-ephedrine. Conversion of all ephedrine isomers required the addition of NAD+ as an oxidant. Without a surplus oxidant or in the presence of NADP+, cell lysates do not significantly convert (pseudo)ephedrine
Results 1 - 8 of 8
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