EC Number |
Natural Substrates |
---|
1.1.1.343 | 6-phospho-D-gluconate + NAD+ |
- |
1.1.1.343 | 6-phospho-D-gluconate + NAD+ |
the enzyme is essential for the biosynthesis of pentose phosphates from glucose-6-phosphate during growth of Haloferax volcanii on glucose as growth substrate |
1.1.1.343 | 6-phospho-D-gluconate + NAD+ |
the wild type enzyme shows very low activity with NAD+, mutations at A30, R31, and T32 increase the catalytic activity with NAD+ |
1.1.1.343 | 6-phospho-D-gluconate + NAD+ |
the enzyme catalyzes an important reaction in the oxidative pentose phosphate pathway, producing a ribose precursor essential for nucleotide and nucleic acid synthesis |