EC Number |
Natural Substrates |
---|
1.1.1.34 | (R)-mevalonate + CoA + 2 NADP+ |
- |
1.1.1.34 | (S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H+ |
- |
1.1.1.34 | (S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H+ |
enzyme is essential for sterol biosynthesis |
1.1.1.34 | (S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H+ |
involved in isopentenyl diphosphate biosynthesis, mevalonate pathway overview |
1.1.1.34 | (S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H+ |
the enzyme is implicated in latex metabolism |
1.1.1.34 | (S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H+ |
HMGR is a key enzyme in the mevalonate pathway of isoprenoid biosynthesis, the sole route in haloarchaea for lipid and carotenoid production |
1.1.1.34 | (S)-3-hydroxy-3-methylglutaryl-CoA + NADPH + H+ |
first step reaction |
1.1.1.34 | 3-hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H+ |
rate-limiting step of cholesterol biosynthesis |
1.1.1.34 | 3-hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H+ |
- |
1.1.1.34 | 3-hydroxy-3-methylglutaryl-CoA + NADPH |
- |