EC Number   |
Natural Substrates |
|---|
    1.1.1.21 | 4-hydroxy-trans-2-nonenal + NADPH + H+ |
- |
| 1.1.1.21 | 4-hydroxynonenal + NADPH + H+ |
- |
| 1.1.1.21 | aldose + NAD(P)H |
- |
| 1.1.1.21 | aldose + NAD(P)H |
wide specificity |
| 1.1.1.21 | aldose + NADPH + H+ |
- |
| 1.1.1.21 | aldose + NADPH + H+ |
first and rate-limiting step in the polyol pathway |
| 1.1.1.21 | aldose + NADPH + H+ |
first and rate-limiting step in the polyol pathway, in which reduction of glucose to sorbitol is coupled with NADPH oxidation |
| 1.1.1.21 | aldose + NADPH + H+ |
first and rate-limiting step in the polyol pathway, in which reduction of glucose to sorbitol is coupled with NADPH oxidation, the enzyme activity is negatively regulated by nitric oxide in the eye lens |
| 1.1.1.21 | aldose + NADPH + H+ |
first and rate-limiting step in the polyol pathway, in which reduction of glucose to sorbitol is coupled with NADPH oxidation, the enzyme activity is negatively regulated by nitric oxide in the eye lens, the activity in diabetic rat lens is increased due to reduced NO concentration, overview |
| 1.1.1.21 | aldose + NADPH + H+ |
first and rate-limiting step in the polyol pathway, pathway network overview |
