Refine search

Search Natural Substrates/ Products (Substrates)

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search
Search for synonyms (with exact matching search term)

Search term:

Results 1 - 10 of 13 > >>
EC Number
Natural Substrates
Commentary (Nat. Sub.)
ATP + biotin + apo-[propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
-
ATP + biotin + apo-[propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
plays an essential role in biotin utilization
ATP + biotin + apo-[propanoyl-CoA:carbon-dioxide ligase (ADP-forming)]
its deficiency causes biotin-responsive multiple carboxylase deficiency in humans
ATP + biotin + apo-[propionyl CoA carboxylase]
-
ATP + biotin + apo-[propionyl-CoA carboxylase]
-
ATP + biotin + apo-[propionyl-CoA:carbon-dioxide ligase (ADP-forming)]
-
ATP + biotin + apocarboxylase
-
ATP + biotin + histone H4
biotinylation at Lys12 especially in telomeric repeats, overview
more
the enzyme is critical to utilization of exogenous or dietary biotin and responds to biotin deprivation by reduction in the steady state level of their mRNAs. The free biotin is directed to brain because the reduction in holocarboxylase synthetase, sodium-dependent multivitamin-transporter and carboxylase mRNAs in liver reduces their capacity to utilize biotin while leaving free biotin in circulation
more
although mammals have multiple biotin-dependent enzymes there is only a single gene encoding holocarboxylase synthetase, HCS, responsible for all cellular biotinylation. The enzyme catalyzes the reactions of EC 6.3.4.10, EC 6.3.4.11, and EC 6.3.4.15, overview
Results 1 - 10 of 13 > >>