EC Number |
Natural Substrates |
---|
3.5.3.1 | L-arginine + H2O |
- |
3.5.3.1 | L-arginine + H2O |
arginase catalyzes the first committed step in the biosynthesis of polyamines |
3.5.3.1 | L-arginine + H2O |
arginase competes with nitric oxide synthases for L-arginine as the common substrate |
3.5.3.1 | more |
arginase II is constitutively expressed in the airways of normal mice, whereas arginase I is undetectable in normal airways, while its expression is increased in airways of mice exposed to ovalbumin |
3.5.3.1 | more |
complex regulation of natural killer cell functions by arginine availability |
3.5.3.1 | L-arginine + H2O |
enzyme is involved in acid resistance and inhibits host nitric oxide production |
3.5.3.1 | L-arginine + H2O |
enzyme is involved in net production of ornithine, a precursor of polyamines, glutamate, and proline, enzyme is also involved in regulation of nitric oxide biosynthesis by modulating arginine availability for nitric oxide synthase |
3.5.3.1 | L-arginine + H2O |
enzyme is involved in regulating L-arginine bioavailability to NO synthase in human penile corpus cavernosum smooth muscle, and in clitoral corpus cavernosum and vagina, enzyme plays a role in both female and male sexual arousal |
3.5.3.1 | L-arginine + H2O |
enzyme is involved in regulation of nitric oxide biosynthesis by modulating arginine availability for nitric oxide synthase |
3.5.3.1 | more |
enzyme may be involved in cellular proliferation in atherosclerosis, inhibiton of enzyme expression by 17beta-estradiol as mechanism in attenuating atherogenensis |