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Results 1 - 8 of 8
EC Number
Natural Substrates
Commentary (Nat. Sub.)
complement C1q zymogen + H2O
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complement component C1s
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complement component C1s
binding of C1 to activator is mediated by C1q and triggers activation of proenzyme C1r into an active protease C1rbar, which in turn activates C1s, thereby initiating the classical pathway of complement
complement component C1s
regulation of the synthesis
complement component C1s
activates the proenzyme form of C1s by limited proteolysis
complement component C1s + H2O
the enzyme is part of the Ca2+-dependent tetramer C1s-C1r-C1r-C1s, termed as C1 complex, which is associated with the recognition molecule C1q, autoactivation of C1r, which then activates proenzyme C1s through cleavage at an Arg-Ile bond in the serine domain, C1r is active in the classical pathway of the complement system
complement component C1s + H2O
the enzyme is part of the Ca2+-dependent tetramer C1s-C1r-C1r-C1s, termed as C1 complex, which is associated with the recognition molecule C1q, autoactivation of C1r, which then activates proenzyme C1s through cleavage at an Arg-Ile bond in the serine domain, C1r is active in the classical pathway of the complement system, interaction anaylsis of the C1 complex and regulatory proteins, overview
zymogen C1s + H2O
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Results 1 - 8 of 8