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Results 1 - 10 of 35 > >>
EC Number
Natural Substrates
Commentary (Nat. Sub.)
(5Z,11Z,14Z)-8,9-epoxyeicosatrienoic acid + H2O
-
(5Z,8Z,11Z)-14,15-epoxyeicosatrienoic acid + H2O
-
(5Z,8Z,14Z)-11,12-epoxyeicosatrienoic acid + H2O
-
(8Z,11Z,14Z)-5,6-epoxyeicosatrienoic acid + H2O
-
16,17-epoxyandrost-4-en-3-one + H2O
high activity
7,12-dimethylbenz[a]anthracene + H2O
-
cis-stilbene oxide + H2O
-
juvenile hormone III + H2O
poor substrate
more
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more
enzyme is induced by a number of xenobiotics, the enzyme is thought to play a detoxifying role by preventing epoxides from reacting irreversibly with critical cellular macromolecules. Some evidence exists to support the hypothesis that microsomal epoxide hydrolase is closely associated with at least certain forms of cytochrome P-450, such association may influence the functional role of the microsomal epoxide hydrolase in the various pathways of bioactivation
Results 1 - 10 of 35 > >>