Refine search

Search Natural Substrates/ Products (Substrates)

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search
Search for synonyms (with exact matching search term)

Search term:

Results 1 - 9 of 9
EC Number
Natural Substrates
Commentary (Nat. Sub.)
dethiobiotin + sulfur
hypothesis: sulfur of biotin is derived from the [Fe-S] center of the enzyme
dethiobiotin + sulfur
catalyzes the last step of the biosynthesis of biotin
dethiobiotin + sulfur
expression of the BIO2 gene appears to be induced under biotin-limiting conditions
dethiobiotin + sulfur
biotin synthase is active for only one turnover, during which the [2Fe-2S]2+ cluster is destroyed, one sulfide from the cluster is incorporated as the biotin thiophane sulfur, while Fe2+ ions and the remaining S2- ion are released from the protein
dethiobiotin + sulfur + 2 S-adenosyl-L-methionine
9-mercaptodethiobiotin is formed as a competent catalytic intermediate by Escherichia coli biotin synthase
dethiobiotin + sulfur + 2 S-adenosyl-L-methionine
The biotin synthase (BioB) reaction does not require pyridoxal phosphate in vivo. Therefore, the biotin sulfur atom cannot be derived via an intrinsic pyridoxal phosphate-dependent BioB cysteine desulfurase activity
dethiobiotin + sulfur + S-adenosyl-L-methionine
-
dethiobiotin + sulfur-(sulfur carrier) + S-adenosyl-L-methionine + reduced [2Fe-2S] ferredoxin
-
more
rate-limiting enzyme for biotin synthesis
Results 1 - 9 of 9