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Results 1 - 6 of 6
EC Number
Natural Substrates
Commentary (Nat. Sub.)
L-cysteine + 'activated' tRNA
L-cysteine + 'activated' tRNA
sulfur deficient tRNA is the natural substrate
L-cysteine + 'activated' tRNA
enzyme is part of the sulfur-transferase system which forms 4-thiouridylate in tRNA
Ctu1 (cytosolic tRNA thiouridilase) associates with the conserved Ctu2 protein and this complex is the wobble uridine-34 thiolase of cytosolic tRNAs in eukaryotes, 2-thiouridylation of tRNAs
tRNA (LYS), but not the tRNA (MET), which has a C at position 34, is thiolated in vivo
sulfide + tRNA-uridine
the enzyme is invoved in biosynthesis of 4-thiouridine in tRNA. 4-Thiouridine, is a modified nucleotide of tRNA that is conserved from bacteria to archaea, where it functions as a sensor for near-UV irradiation
Results 1 - 6 of 6