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Results 1 - 10 of 10

EC Number	Natural Substrates	Commentary (Nat. Sub.)
1.5.99.4	(R)-nicotine + acceptor + H2O	-
1.5.99.4	(S)-nicotine + acceptor + H2O	via N-methylmyosmine, which then spontaneously hydrolyzes to pseudooxynicotine. The two enantiomers are degraded at approximately the same rate, indicating that NOX does not show chiral selectivity
1.5.99.4	D-nicotine + acceptor + H2O	isozyme specific for the D-isomer
1.5.99.4	DL-nicotine + ?	first enzyme in nicotine pathway
1.5.99.4	L-nicotine + acceptor + H2O	isozyme strictly specific for the L-isomer
1.5.99.4	more	enzyme expression and activity is regulated by substrate and product level via transcription repressor HdnoR
1.5.99.4	more	organism can grow on L-nicotine since it is converted to D-nicotine by a racemase
1.5.99.4	nicotine + acceptor + H2O	-
1.5.99.4	nicotine + acceptor + H2O	first enzyme in the nicotine degradation pathway
1.5.99.4	nornicotine + acceptor + H2O	-

Results 1 - 10 of 10

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Release 2023.1 (January 2023)