EC Number   |
Natural Substrates  |
|---|
    1.5.5.2 | L-proline + a quinone |
- |
| 1.5.5.2 | L-proline + a quinone |
the reverse reaction is catalyzed by pyrroline-5-carboxylate reductase, EC 1.5.1.2 |
| 1.5.5.2 | L-proline + acceptor |
- |
| 1.5.5.2 | L-proline + acceptor |
the bifunctional enzyme catalyzes the oxidation of proline in two steps. (S)-1-Pyrroline-5-carboxylate, the product of the first reaction is in spontaneous equilibrium with its tautomer L-glutamate gamma-semialdehyde: (1) L-proline + acceptor = (S)-1-pyrroline-5-carboxylate + reduced acceptor, (2) L-glutamate 5-semialdehyde + NAD+ + H2O = L-glutamate + NADH + H+ |
| 1.5.5.2 | L-proline + acceptor + H2O |
- |
| 1.5.5.2 | L-proline + acceptor + H2O |
PutA flavoprotein plays multiple roles in proline catabolism by functioning as a membrane-associated bi-functional enzyme and a transcriptional repressor of proline utilization genes |
| 1.5.5.2 | L-proline + acceptor + H2O |
the enzyme catalyzes the first step of proline catabolism |
| 1.5.5.2 | L-proline + oxidized phenazine methosulfate |
- |
