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Results 1 - 10 of 11 > >>
EC Number
Natural Substrates
Commentary (Nat. Sub.)
cholesterol + AH2 + O2
-
cholesterol + AH2 + O2
cholesterol 25-hydroxylase has the capacity to play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein processing and ultimately leads to inhibition of gene transcription
cholesterol + AH2 + O2
genetic variability in the set of cholesterol metabolism genes: cholesterol 25-hydroxylase, cholesterol 24-hydroxylase and ATP-binding cassette transporter A1 does not influence the development of Alzheimer‘s disease
cholesterol + AH2 + O2
testicular macrophagers play an important role in the differentiation of Leydig cells through the secretion of 25-hydroxycholesterol
cholesterol + AH2 + O2
the enzyme has the capacity to synthesize an active and potent regulator of the sterol response element binding protein pathway within the cell
cholesterol + AH2 + O2
lower 25-hydroxylation enzyme activity by CYP1A2 compared to marker enzyme CYP3A4
cholesterol + AH2 + O2
lower 25-hydroxylation enzyme activity by CYP2C9 compared to marker enzyme CYP3A4
cholesterol + AH2 + O2
lower 25-hydroxylation enzyme activity by CYP2D6 compared to marker enzyme CYP3A4
cholesterol + AH2 + O2
production of 25-hydroxycholesterol by intact CYP3A4, most significant activity is 25-hydroxylation, which is higher than that of 4beta-hydroxylation, a marker activity of CYP3A4
cholesterol + AH2 + O2
the reaction might be catalyzed by CYP3A4
Results 1 - 10 of 11 > >>