EC Number   |
Natural Substrates |
|---|
   6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
RNA editing, posttranscriptional RNA processing in which uridylate residues are inserted into and deleted from pre-mRNAs to create start and stop codons, also acts to reseal mRNAs cleaved at incorrect sites |
| 6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
RNA editing, unique U insertion and U deletion process, involves cycles of pre-mRNA cleavage, terminal U addition or U removal, and religation, band IV is the RNA editing ligase needed to seal in U deletion |
| 6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
RNA-editing |
| 6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
the enzyme is essential for survival of both insect and bloodstream forms of the parasite |
| 6.5.1.3 | more |
the group I intron from cyanobacterium Anabaena sp. catalyzes phosphodiester bond formation using a triphosphate on the 5'-terminal nucleotide, much like protein polymerases and engineered ribozymes. In the process, this ribozyme forms a unique circular RNA that incorporates the exogenous guanosine cofactor added during self-splicing |
| 6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
the L1 ligase is regioselective for formation of the biologically relevant 5' to 3' phosphodiester bond rather than a 5' to 2' bond |
| 6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
Trl1 executes the end-healing and end-sealing steps of tRNA splicing, requires a 2'-PO4 end for tRNA splicing in vivo |
