EC Number   |
Natural Substrates |
|---|
    3.5.3.1 | more |
hereditary defects in arginase compromise structure and catalysis, which results in an accumulation of arginine in the blood known as hyperarginemia. Arginase deficiency can also result in the accumulation of nitrogen in the form of ammonia, which results in hyperammonemia |
| 3.5.3.1 | more |
infection of mice with Schistosoma mansoni cercariae elevates arginase activity |
| 3.5.3.1 | more |
mitochondrial isoform arginase II negatively regulates NO synthase 1 activity by limiting substrate availability in its microdomain |
| 3.5.3.1 | more |
presence of arginine pools, which are accessible to NO synthase and enzyme, but not exchangeable |
| 3.5.3.1 | more |
recombinant human arginase I (rhArg-PEG), an arginine-depleting enzyme, can inhibit the growth of arginine-dependent tumors |
| 3.5.3.1 | L-arginine + H2O |
the enzyme catalyses the catabolism of L-arginine to L-ornithine and urea |
| 3.5.3.1 | L-arginine + H2O |
the enzyme involved in urea cycle |
| 3.5.3.1 | more |
the wild type enzyme does not hydrolyze 1-amino-4-guanidinobutane (agmatine) |
