EC Number |
Natural Substrates |
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3.4.15.1 | more |
the enzyme may play a role not only in the angiotensin-bradykinin system but also in the metabolism of circulating enkephalins and other bioactive peptides |
3.4.15.1 | more |
plays a role in blood pressure regulation |
3.4.15.1 | more |
angiotensin-converting enzyme-2 is a regulatory protein of the renin-angiotensin system. ACE2 interacts with calmodulin and this association down-regulates shedding of the ACE2 ectodomain |
3.4.15.1 | more |
neutral endopeptidase and angiotensin converting enzyme do not have additive effects regarding neuropeptide degradation |
3.4.15.1 | more |
somatic angiotensin I-converting enzyme plays a central role in blood pressure regulation |
3.4.15.1 | more |
ACE is a key regulator of blood pressure homeostasis |
3.4.15.1 | more |
ACE may influence trypsin biosynthesis in the larval gut by interacting with a trypsin-modulating oostatic factor |
3.4.15.1 | more |
ACE may play a role in human epidermis morphogenesis during fetal life and serve as an unrecognized marker for keratinocyte progenitor cells |
3.4.15.1 | more |
ACE degrades bradykinin, other vasoactive peptides, and activates angiotensin |
3.4.15.1 | more |
AnCE is a single domain protein with ACE activity, an ACE homologue |