EC Number |
Natural Substrates |
---|
2.3.1.48 | acetyl-CoA + [PGC-1alpha]-L-lysine |
- |
2.3.1.48 | acetyl-CoA + [PGC-1]-L-lysine |
- |
2.3.1.48 | acetyl-CoA + [protein]-L-lysine |
- |
2.3.1.48 | acetyl-CoA + [protein]-L-lysine |
endogenous GCN5 and EGR2 in iNKT cells |
2.3.1.48 | acetyl-CoA + [PTEN]-L-lysine |
acetylation of the oncosuppressor protein PTEN on two lysine residues (Lys125 and Lys128) |
2.3.1.48 | acetyl-CoA + [STAT3]-L-lysine |
- |
2.3.1.48 | acetyl-CoA + [TIP5]-L-lysine |
- |
2.3.1.48 | acetyl-CoA + [TRRAP]-L-lysine |
- |
2.3.1.48 | androgen receptor + acetyl-CoA |
receptor signaling in prostate cancer cells is augmented by the androgen receptor coactivator p300, which transactivates and acetylates the androgen receptor in the presence of 100 nM dihydrotestosterone, involvement of p300 in neuropeptide activation of androgen receptor signaling, overview |
2.3.1.48 | ATM kinase + acetyl-CoA |
ATM protein kinase regulates the cells response to DNA damage through the phosphorylation of proteins involved in cell-cycle checkpoints and DNA repair, suppression of Tip60 blocks the activation of ATMs kinase activity, ATM autophosphorylation e.g. at Ser1981, and prevents the ATM-dependent phosphorylation of p53 and chk2, inactivation of Tip60 sensitizes cells to ionizing radiation, overview |