EC Number   |
Natural Substrates  |
|---|
   2.3.1.48 | acetyl-CoA + histone H3 |
acetylation of Lys14 by tGCN5 in the consensus sequence QTARKSTGGK14APRKLASK |
| 2.3.1.48 | acetyl-CoA + histone H3 |
acetylation of Lys56 |
| 2.3.1.48 | acetyl-CoA + histone H3 |
CBP binds and acetylates histones at neural promoters, and regulates Corpus Callosum development. CBP binds to neuronal and glial promoters and globally promotes histone acetylation in the embryonic cortex, e.g. the beta-actin promoter, overview |
| 2.3.1.48 | acetyl-CoA + histone H3 |
H4R3 methylation, catalyzed by PRMT1, facilitates beta-globin transcription by regulating histone acetyltransferase binding, and histone H3 and H4 acetylation, overview |
| 2.3.1.48 | acetyl-CoA + histone H3 |
regulation, detailed overview. Acetylation and deacetylation events, in combination with other post-translational protein modifications, generate an NF-kappaB-signaling code and regulate NF-kappaB-dependent gene transcription in an inducer- and promoter-dependent manner, overview |
| 2.3.1.48 | acetyl-CoA + histone H3 |
Rtt109 association with distinct histone chaperones directs substrate selection between N-terminal lysines, H3K9, H3K23, and those within the histone fold domain, H3K56 |
| 2.3.1.48 | acetyl-CoA + histone H3 |
Rtt109 is specific for histone H3, acetylation at Lys9 and Lys56. RTT109 has functions in addition to maintaining genome stability |
| 2.3.1.48 | acetyl-CoA + histone H3 |
acetylation at Lys18 |
| 2.3.1.48 | acetyl-CoA + histone H3 |
acetylation of Lys23 |
| 2.3.1.48 | acetyl-CoA + histone H3 |
acetylation of Lys9, Lys14, Lys18, Lys23, Lys27, Lys36, and Lys37 |
