EC Number |
Natural Substrates |
---|
1.17.1.9 | formate + NAD+ |
any one of the three formate dehydrogenases Fdh1, Fdh2 or Fdh3 is sufficient to sustain growth on formate. None is required for growth on methanol or methylamine |
1.17.1.9 | formate + NAD+ |
role of formate dehydrogenase in detoxification of exogenous formate |
1.17.1.9 | formate + NAD+ |
the enzyme shows strict substrate specificity for formate |
1.17.1.9 | formate + NAD+ |
the enzyme exhibits a dramatic preference for the CO2 reduction reaction over the oxidation reaction of formate |
1.17.1.9 | formate + NADP+ |
- |
1.17.1.9 | formate + NADP+ |
NADP+ is substrate for several mutant enzymes |
1.17.1.9 | formate + NADP+ |
NADP+ is a substrate for mutant enzymes only |
1.17.1.9 | more |
S-formylglutathione rather than free formate is an intermediate in oxidation of methanol by yeast |
1.17.1.9 | more |
possible role of enzyme in oxalate metabolism |
1.17.1.9 | more |
the enzyme shows no activity when methanol, ethanol, formaldehyde, sodium acetate, sodium malate, sodium oxalate, sodium lactate, sodium succinate, sodium citrate and sodium nitrate are used as the sole substrate |