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EC Number
Natural Substrates
Commentary (Nat. Sub.)
PKA regulates beta2-integrin avidity activation via a MLCK-dependent pathway, overview
postnatal decreases in vascular reactivity involve decreases in the thick filament component of myofilament calcium sensitivity, which is measured as the relationship between cytosolic calcium concentration and myosin light chain phosphorylation, relations between myosin light chain phosphorylation and contractile force, overview
the enzyme is involved in inflammation response, including apoptosis, vascular permeability, and leukocyte diapedesis. Single nucleotide polymorphisms are involved in the risk of sepsis-related acute lung injury and asthma
14-3-3 binding of nmMLCK
non-muscle myosin and smooth muscle myosin are the only known substrates of MLCK in vivo
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