EC Number   |
Natural Substrates  |
|---|
   2.4.1.90 | UDPgalactose + N-acetylglucosaminyl at the non-reducing ends of protein-bound oligosaccharides |
biosynthesis of carbohydrate moieties of glycoproteins and glycolipids, role in intercellular recognition and adhesion |
| 2.4.1.90 | UDPgalactose + N-acetylglucosaminyl at the non-reducing ends of protein-bound oligosaccharides |
main enzyme responsible for the transfer of galactose residues from UDPgalactose into terminal N-acetylglucosamine residues of complex-type oligosaccharides in newly synthesized glycoproteins in the Golgi apparatus. Deficiency of UDP-galactose:N-acetylglucosamine beta-1,4-galactosyltransferase I causes the congenital disorder of glycosylation type IId, a severe neurologic disease characterized by a hydrocephalus, myopathy and blood-clotting defects |
| 2.4.1.90 | UDPgalactose + N-acetylglucosaminyl at the non-reducing ends of protein-bound oligosaccharides |
biosynthesis of keratan sulfate-like polysaccharides |
