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EC Number
Natural Substrates
Commentary (Nat. Sub.)
UDPgalactose + N-acetylglucosaminyl at the non-reducing ends of protein-bound oligosaccharides
biosynthesis of carbohydrate moieties of glycoproteins and glycolipids, role in intercellular recognition and adhesion
UDPgalactose + N-acetylglucosaminyl at the non-reducing ends of protein-bound oligosaccharides
main enzyme responsible for the transfer of galactose residues from UDPgalactose into terminal N-acetylglucosamine residues of complex-type oligosaccharides in newly synthesized glycoproteins in the Golgi apparatus. Deficiency of UDP-galactose:N-acetylglucosamine beta-1,4-galactosyltransferase I causes the congenital disorder of glycosylation type IId, a severe neurologic disease characterized by a hydrocephalus, myopathy and blood-clotting defects
UDPgalactose + N-acetylglucosaminyl at the non-reducing ends of protein-bound oligosaccharides
biosynthesis of keratan sulfate-like polysaccharides
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