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EC Number
Metals/Ions
Commentary
Reference
4.6.1.24
Ca2+
the enzyme has six binding sites for the cation
655420
4.6.1.24
H+
the cation produces two different tautomers of the histidine residues His53 and His85
656509
4.6.1.24
Mg2+
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683135
4.6.1.24
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Chalaropsis sp., no metal ion requirement
24214
4.6.1.24
Sr2+
the enzyme contains a divalent ion-binding site involving Asp49, with preference for this cation. The ion binding at this site stabilizes the protein
655420
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