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Results 1 - 8 of 8
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EC Number Metals/Ions Commentary Reference
Show all pathways known for 4.2.2.21Display the word mapDisplay the reaction diagram Show all sequences 4.2.2.21Ca2+ - 34086
Show all pathways known for 4.2.2.21Display the word mapDisplay the reaction diagram Show all sequences 4.2.2.21Ca2+ addition of Mg2+ or Ca2+ has a dramatically different effect on activity toward CS (glucuronic acid) and DS (iduronic acid). The specific activity for CS substrates increases only moderately (2fold) while an increase of 25fold is observed for DS 692529
Show all pathways known for 4.2.2.21Display the word mapDisplay the reaction diagram Show all sequences 4.2.2.21Ca2+ stimulates activity, particularly against dermatan sulfate 690969
Show all pathways known for 4.2.2.21Display the word mapDisplay the reaction diagram Show all sequences 4.2.2.21Mg2+ - 34086
Show all pathways known for 4.2.2.21Display the word mapDisplay the reaction diagram Show all sequences 4.2.2.21Mg2+ addition of Mg2+ or Ca2+ has a dramatically different effect on activity toward CS (glucuronic acid) and DS (iduronic acid). The specific activity for CS substrates increases only moderately (2fold) while an increase of 25fold is observed for DS 692529
Show all pathways known for 4.2.2.21Display the word mapDisplay the reaction diagram Show all sequences 4.2.2.21Mg2+ stimulates activity, particularly against dermatan sulfate 690969
Show all pathways known for 4.2.2.21Display the word mapDisplay the reaction diagram Show all sequences 4.2.2.21Mn2+ - 34086
Show all pathways known for 4.2.2.21Display the word mapDisplay the reaction diagram Show all sequences 4.2.2.21more for the monovalent ions tested, increasing the concentration of Na+, K+, or CS+ chloride from 0 to 0.1 M increases the activity against all substrates. Further increases in salt concentration reduces the activity dramatically, with 50% inhibition occurring at 0.15 M and a nearly complete inhibition at 0.4 M salt 690969
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