EC Number |
Metals/Ions |
Reference |
---|
4.2.1.19 | Mg2+ |
metalloprotein, transition metals induce aggregation and are required for catalysis, 1 equivalent of Mn2+ per subunit induces the formation of 24-mers from the trimeric enzyme |
652527 |
4.2.1.19 | Mn |
the manganese cluster is critical in converting the inactive trimeric state of the enzyme into its biologically active 24-mer and also forms the active site. The substrate is bound to the manganese cluster as an imidazole moiety that subsequently collapse to yield a diazafulvene intermediate |
666944 |
4.2.1.19 | Mn2+ |
0.5 mM enhances the activity 7fold |
5540 |
4.2.1.19 | Mn2+ |
activity dependent on |
5533 |
4.2.1.19 | Mn2+ |
contains two Mn2+ ions, 0.05 mM Mn2+ used in assay conditions |
728872 |
4.2.1.19 | Mn2+ |
essential for assembly of subunits |
5546 |
4.2.1.19 | Mn2+ |
Km: 0.0073 mM |
5535 |
4.2.1.19 | Mn2+ |
Km: 0.0076 mM |
5534 |
4.2.1.19 | more |
not activated by Mg2+, Ni2+, Cd2+, Fe2+, Co2+ |
5538 |
4.2.1.19 | more |
not activated by Mg2+, Ni2+, Cd2+, Fe2+, Co2+, Fe3+ |
5540 |