EC Number   |
Metals/Ions |
Reference |
|---|
   3.6.5.2 | Ca2+ |
activates |
720356 |
| 3.6.5.2 | Ca2+ |
required |
755731 |
| 3.6.5.2 | Mg2+ |
1 mM required for optimal activity, involved in binding of beta- and gamma-phosphates of GTP |
644112 |
| 3.6.5.2 | Mg2+ |
coordinated to oxygens of beta- and gamma-phosphates of GTP, essential for GTP hydrolysis |
644137 |
| 3.6.5.2 | Mg2+ |
in absence of Mg2+ rapid release of GDP but dissociation rate of GTP very slow |
644132 |
| 3.6.5.2 | Mg2+ |
nucleotide binding to Ras is greatly enhanced by Mg2+ |
733077 |
| 3.6.5.2 | Mg2+ |
octahedrally coordinated |
644120 |
| 3.6.5.2 | Mg2+ |
octahedrally coordinated within the P-loop region |
644118 |
| 3.6.5.2 | Mg2+ |
required |
733638, 734276, 734361, 734659, 734730, 735220, 755731, 756101, 756339, 756995, 758125, 758300 |
| 3.6.5.2 | Mg2+ |
required, binding structure analysis |
734036 |
