EC Number |
Metals/Ions |
Reference |
---|
3.6.1.23 | Co2+ |
activates to 72% of the activity with Mg2+ |
670775 |
3.6.1.23 | Co2+ |
can partially replace Mg2+, causes increase in Km |
657286 |
3.6.1.23 | Co2+ |
can substitute the physiological cofactor Mg2+, however the kcat is significantly reduced compared to dUTP-Mg2+ |
696412 |
3.6.1.23 | Co2+ |
strictly dependent on a bivalent metal cation like Co2+ |
718787 |
3.6.1.23 | Mg2+ |
- |
667399, 667783, 669790, 669804, 670909, 685380, 686744, 689949 |
3.6.1.23 | Mg2+ |
0.5 mM, stimulates by 7% |
209977 |
3.6.1.23 | Mg2+ |
5 mM used in assay conditions |
756317 |
3.6.1.23 | Mg2+ |
activates |
696282, 699236 |
3.6.1.23 | Mg2+ |
activates, phosphate chain coordination involves Mg2+, binding structure, overview. Mg2+ probably dissociates from the enzyme with the product PPi and not with dUMP |
695290 |
3.6.1.23 | Mg2+ |
best divalent cation, bound at the center of the trimeric enzyme structure |
670091 |