EC Number   |
Metals/Ions |
Reference |
|---|
   3.4.24.69 | more |
no involvement of cobalt, copper, iron, manganese or nickel, atomic absorption spectroscopy |
31427, 31440 |
| 3.4.24.69 | more |
the C2II channel is cation-selective |
683678 |
| 3.4.24.69 | Zinc |
0.8-1 gatom zinc/mol neurotoxin |
31426 |
| 3.4.24.69 | Zinc |
1 atom of zinc per molecule botulinum neurotoxin (MW 150000, of serotypes A, B and E, each in 2-chain form) |
31427 |
| 3.4.24.69 | Zinc |
1 atom of zinc per molecule botulinum neurotoxin, bound to light chain (i.e. L-chain) |
31425, 31440 |
| 3.4.24.69 | Zinc |
activation requires reduction of interchain disulfide bond |
31424, 31441 |
| 3.4.24.69 | Zinc |
atom absorption spectroscopy |
31425, 31426, 31427, 31440 |
| 3.4.24.69 | Zinc |
contains zinc binding motif of metalloendopeptidases His-Glu-X-X-His |
31425, 31427, 31441 |
| 3.4.24.69 | Zinc |
contains zinc binding motif of metalloendopeptidases His223-Glu-Leu-Ile-His-X-X-His230 |
31436 |
| 3.4.24.69 | Zinc |
evidence for noncanonical zinc protease activity |
670666 |
