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EC Number
Metals/Ions
Commentary
Reference
3.4.11.9
Ca2+
0.5-1.0 mM, slight activation
36044
3.4.11.9
Ca2+
activates slightly
753683
3.4.11.9
Ca2+
activates the enzyme at concentrations of 0.01-0.1 mM with substrate substance P, inhibits above 1 mM
651792
3.4.11.9
Ca2+
enzyme bound
754700
3.4.11.9
Ca2+
slight activation at 10 mM
754215
3.4.11.9
Ca2+
stimulation of enzyme activity at 0.4 mM, inhibition at 4 mM
652158
3.4.11.9
Cd2+
activates
35949
3.4.11.9
Co2+
0.03 mM, activates
36044
3.4.11.9
Co2+
10 mM, moderate inhibitory effect
731113
3.4.11.9
Co2+
activates
36050
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