EC Number |
Metals/Ions |
Reference |
---|
2.7.7.44 | Ca2+ |
36% of the activation with Mg2+ |
645282 |
2.7.7.44 | Co2+ |
40% of the activation with Mg2+ |
645282 |
2.7.7.44 | Mg2+ |
- |
670505 |
2.7.7.44 | Mg2+ |
best fulfills the requirement for a divalent cation, maximal activity of forward reaction at a Mg2+/UTP ratio of 2:1. In the reverse reaction below 5 mM diphosphate, a Mg2+:diphosphate ratio of approximately 1:1 gives optimal activity, excess of Mg2+ is inhibitory |
645282 |
2.7.7.44 | Mg2+ |
maximum activity in the presence of Mg2+. 20 mM used in assay conditions |
760379 |
2.7.7.44 | Mg2+ |
required |
645283 |
2.7.7.44 | Mn2+ |
can substitute for Mg2+ in either the forward or the reverse direction, 53% of the activation with Mg2+, excess of Mn2+ inhibits the reaction in both directions |
645282 |
2.7.7.44 | Zn2+ |
37% of the activation with Mg2+ |
645282 |