EC Number   |
Metals/Ions |
Reference |
|---|
   2.7.11.31 | Ca2+ |
- |
644958 |
| 2.7.11.31 | Ca2+ |
activation of AMPK is mediated by a CO2-triggered increase in intracellular Ca2+ concentration and Ca2+/calmodulin-dependent kinase kinase-beta, CaMKK-beta |
693356 |
| 2.7.11.31 | Ca2+ |
AMPK activation by phosphorylation through the Ca2+-calmodulin dependent protein kinase kinase, CaMKK |
692170 |
| 2.7.11.31 | Ca2+ |
increases in intracellular Ca2+ levels activate AMPK is via the activation of CaMKKs, mechanism, overview |
691704 |
| 2.7.11.31 | Mg2+ |
- |
644955, 644959, 665496, 684366, 687732, 690346, 690657, 690725, 690726, 691132, 691165, 691556, 691621, 691704, 692000, 692001, 692091, 692170, 692195, 692277, 692365, 692682, 692814, 693032, 693047, 693080, 693151, 693205, 693207, 693328, 693356, 693405, 693845, 694825, 703277 |
| 2.7.11.31 | Mg2+ |
5 mM used in assay conditions |
761360 |
| 2.7.11.31 | Mg2+ |
Asp-157 within the DFG motif is required for binding the Mg2+ ion that co-ordinates beta and gamma phosphates of Mg2+-ATP in the active site |
701572 |
| 2.7.11.31 | Mg2+ |
required |
739785, 739978, 740018, 740280, 741016, 741365 |
| 2.7.11.31 | Mg2+ |
requirement, actual substrate: MgATP2- |
286565, 644953, 644971, 644972, 644973, 644975 |
| 2.7.11.31 | Mn2+ |
- |
703277 |
