EC Number |
Metals/Ions |
Reference |
---|
2.7.11.14 | Ca2+ |
affects enzyme binding to rhodopsin, induces binding of recoverin to the enzyme inhibiting its activity, NMR structure determination and analysis of the ternary complex RK25-Ca2+-recoverin |
674709 |
2.7.11.14 | Ca2+ |
Ca2+ controls the binding of recoverin to the enzyme |
760605 |
2.7.11.14 | Ca2+ |
Ca2+-dependent phosphorylation of arrestin, Ca2+ concentrations above 0.0025 mM free Ca2+ stimulate, maximal at 0.05 mM Ca2+, Ca2+ may facilitate arrestin-binding to RK, phosphorylation of rhodopsin is not Ca2+-dependent |
640713 |
2.7.11.14 | Ca2+ |
controls the binding of recoverin to the enzyme |
664267 |
2.7.11.14 | Ca2+ |
dependent on, rhodopsin phosphorylation in rod outer segment membranes |
665584 |
2.7.11.14 | Ca2+ |
enzyme activity requires light-activation, Ca2+ and membranes |
675513 |
2.7.11.14 | Ca2+ |
GRK1 activity is inhibited by binding of the Ca2+-bound form of S-modulin/recoverin |
689386 |
2.7.11.14 | Ca2+ |
induces a conformational change, while in the calciumfree form, the myristoyl group is held within a hydrophobic cleft, addition of calcium leads to its release and to membrane binding, inhibits rhodopsin binding to the enzyme via recoverin, which binds to the amphipathic peptide at the N-terminus of the enzyme and blocks rhodopsin binding |
674596 |
2.7.11.14 | Ca2+ |
regulation of the rhodopsin activity by recoverin and calmodulin is Ca2+-dependent |
725081 |
2.7.11.14 | Mg2+ |
- |
490797, 490997, 491015, 640709, 640710, 640711, 640712, 640713, 640714, 640716, 640717, 640718, 640719, 640720, 640722, 640723, 640724, 640725, 640726, 640727, 640728, 640729, 640730, 662393, 663926, 664267, 665584, 666708, 674596, 675513, 675527, 676271, 687706, 689386 |