EC Number |
Metals/Ions |
Reference |
---|
2.3.3.14 | Co2+ |
- |
704600 |
2.3.3.14 | Mg2+ |
0.002 mM MgCl2 has no effect |
488137 |
2.3.3.14 | Mg2+ |
about 10% stimulation, no absolute requirement |
488136 |
2.3.3.14 | Mg2+ |
activates |
719956 |
2.3.3.14 | Mg2+ |
required |
488135 |
2.3.3.14 | Mn2+ |
activates |
719956 |
2.3.3.14 | more |
enzyme activity is independent of any metal ions |
719384 |
2.3.3.14 | more |
not activated by 50 mM Zn2+, 5 mM Ni2+ and 5 mM Co2+ |
719956 |
2.3.3.14 | Na+ |
activator at low concentrations, inhibitor at high concentrations, inhibition and activation can occur simultaneously, inhibition by Na+ is eliminated at high concentrations of acetyl-CoA |
662403 |
2.3.3.14 | Na+ |
activity is simultaneously inhibited and activated. Activation by Na+ binding to the active enzyme conformer at an allosteric site. Inhibition by binding to the active site |
662404 |