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EC Number	Metals/Ions	Commentary	Reference
1.4.1.2	Al3+	enhances increase in GDH activity due to Hg	673970
1.4.1.2	betaine	high concentrations of salt may be substituted with 30% DMSO or betaine with good stability and activity	724935
1.4.1.2	Ca2+	a putative EF-hand loop motif, which binds Ca2+ in the GDH2 and GDH3 proteins, but absent in GDH1	670544
1.4.1.2	Ca2+	activation	391573, 391574, 391583
1.4.1.2	Ca2+	activation of amination, no effect on deamination	391561
1.4.1.2	Ca2+	activation of partially purified enzyme	391569
1.4.1.2	Ca2+	activation of reductive amination	391546
1.4.1.2	Ca2+	amination is stimulated, deamination not influenced	391572
1.4.1.2	Ca2+	required	391568, 763741
1.4.1.2	Ca2+	slight inhibition of oxidative deamination	391546

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Release 2023.1 (January 2023)