EC Number   |
Metals/Ions |
Reference |
|---|
  1.13.11.78 | Ca2+ |
partial activation compared to Fe2+ |
729889 |
| 1.13.11.78 | Co2+ |
partial activation compared to Fe2+ |
729889 |
| 1.13.11.78 | Cu2+ |
partial activation compared to Fe2+ |
729889 |
| 1.13.11.78 | Fe2+ |
dependent on |
756059, 764169 |
| 1.13.11.78 | Fe2+ |
dependent on, contains 1.2 mol of iron per mole of enzyme |
729889 |
| 1.13.11.78 | Fe2+ |
nonheme diiron oxygenase |
763794 |
| 1.13.11.78 | Fe2+ |
required and involvedin catalysis. PhnZ is a nonheme diiron oxygenase |
743907 |
| 1.13.11.78 | Fe2+ |
required for catalysis, the enzyme uses a diiron oxygenase mechanism. Residue Y24 forms a transient ligand interaction at the dioxygen binding site of the two Fe2+. The first Fe ion is coordinated in a distorted octahedral geometry by Y24, H34, H58, D59, D161, and the bridging water. PhnZ ligates the second Fe2+ ion in an octahedral geometry through interactions with D59, H80, H104, and the bridging water. The second Fe is further coordinated in a bidentate fashion by the adjacent carboxylate and alpha-hydroxyl oxygens of L-tartrate |
743680 |
| 1.13.11.78 | Fe3+ |
partial activation compared to Fe2+ |
729889 |
| 1.13.11.78 | Iron |
the enzyme contains 1.2 Fe per monomer, contains a dinuclear iron cluster. The mixed-valent FeII/FeIII state is the catalytically active cofactor form |
730821 |
