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EC Number
Metals/Ions
Commentary
Reference
Mg2+
-
Mg2+
activates, optimum: 5-10 mM
Mn2+
activates, showing slightly higher activity than Mg2+
more
calcium, cobalt, copper, cadmium, nickel, and zinc are ineffective
Mg2+
dependent on
Mg2+
divalent cation required
Mn2+
enzyme activity is optimal at 2.5 mM Mn2+
Mg2+
enzyme activity is optimal at 5 mM Mg2+
Mg2+
Km: 0.4 mM, inhibition above 10 mM; required
Mg2+
L1 ligase is an obligate metalloenzyme that is highly specific for Mg2+. It is selected in the presence of 60 mM MgCl2 and functions optimally in Mg2+ concentrations as high as 100 mM
Results 1 - 10 of 22 > >>