EC Number   |
Metals/Ions |
Reference |
|---|
    4.1.3.1 | Mg2+ |
- |
33131, 33134, 33138 |
| 4.1.3.1 | Mg2+ |
10 mM, dependent |
638504, 651215 |
| 4.1.3.1 | Mn2+ |
5 mM, 45% activity, binds and stabilizes non-catalytic alpha/beta barrel core without structural alterations (revealed by thermal, urea and GdnHCL denaturation and far-UV CD) |
701127 |
| 4.1.3.1 | Zn2+ |
5 mM, 90% inhibition of Mg2+-activated enzyme, interaction with catalytic domain induces partial unfolding (revealed by thermal denaturation, far-UV circular dichroism, ANS fluorescence spectra, and glutaraldehyde crosslinking) |
701127 |
| 4.1.3.1 | Cd2+ |
5 mM, 90% inhibition of Mg2+-activated enzyme, interaction with catalytic domain induces partial unfolding (revealed by thermal denaturation, far-UV circular dichroism, fluorescence spectra, and glutaraldehyde crosslinking) |
701127 |
| 4.1.3.1 | Mg2+ |
5 mM, essential for catalytic activity, 100% activity, binds and stabilizes non-catalytic alpha/beta barrel core without structural alterations (revealed by thermal, urea and GdnHCL denaturation and far-UV CD) |
701127 |
| 4.1.3.1 | Mg2+ |
absolute requirement |
33135 |
| 4.1.3.1 | Co2+ |
activating |
664083 |
| 4.1.3.1 | Fe2+ |
activating |
664083 |
| 4.1.3.1 | Mg2+ |
activating oxalacetate hydrolase activity |
664083 |
