EC Number   |
Metals/Ions |
Reference |
|---|
    3.6.1.67 | Mg2+ |
dependent on |
758154 |
| 3.6.1.67 | Mg2+ |
divalent cations are rerquired for the enzyme to function. Maximal activation is achieved with 8 mM Mg2+. Zn2+ and Ca2+ (both at 8 mM) are 2.4% and 7.1%, respectively, as effective as Mg2+. Mn2+ can not be tested because 7,8-dihydroneopterin triphosphate is rapidly and nonenzymatically decomposed in the presence of Mn2+ |
727800 |
| 3.6.1.67 | Co2+ |
excellent mimic of Mg2+ |
758154 |
| 3.6.1.67 | Ni2+ |
excellent mimic of Mg2+ |
758154 |
| 3.6.1.67 | Mg2+ |
maximal activation is achieved with 8 nM Mg2+. Zn2+ and Ca2+ (both at 8 mM) are 2.4% and 7.1%, respectively, as effective as Mg2 |
727800 |
| 3.6.1.67 | Mg2+ |
required, no activity with Ca2+ |
727852 |
| 3.6.1.67 | Mg2+ |
requires a physiological level (approximately 1 mM) of Mg2+ |
727852 |
| 3.6.1.67 | Mg2+ |
the enzyme requires a physiological level of Mg2+, 70% of its maximal activity is reached at 1 mM Mg2+. No activation by 1 mM Ca2+ |
727852 |
