EC Number   |
Metals/Ions  |
Reference |
|---|
    3.6.1.41 | Ca2+ |
no effect |
246770 |
| 3.6.1.41 | Ca2+ |
weak stimulation in absence of other divalent metal ions, high synergistic stimulation in combination with Co2+ at its suboptimal concentration |
246765 |
| 3.6.1.41 | Cd2+ |
0.002-0.005 mM, 3.5fold stimulation |
246765 |
| 3.6.1.41 | Co2+ |
0.1-0.5 mM, 100fold increase of activity |
246765 |
| 3.6.1.41 | Co2+ |
2500fold stimulation |
246770 |
| 3.6.1.41 | Co2+ |
about 50% of the activity with Mn2+. In the presence of Mn2+, PrpA hydrolyzes P1,P5-bis(adenosyl)tetraphosphate mainly into AMP and ATP, whereas in the presence of Co2+ PrpA hydrolyzes P1,P5-bis(adenosyl)tetraphosphate into two molecules of ADP, reaction of EC 3.6.1.17 |
733872 |
| 3.6.1.41 | Co2+ |
required for ApnA hydrolysis |
733872 |
| 3.6.1.41 | Co2+ |
symmetrical Ap4A hydrolase is Co2+-dependent |
697896 |
| 3.6.1.41 | Mg2+ |
weak stimulation in absence of other divalent metal ions, high synergistic stimulation in combination with Co2+ at its suboptimal concentrations |
246765 |
| 3.6.1.41 | Mn2+ |
0.2-0.5 mM, 8fold stimulation |
246765 |
