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Results 1 - 10 of 12 > >>
EC Number
Metals/Ions
Commentary
Reference
Ca2+
no effect
Ca2+
weak stimulation in absence of other divalent metal ions, high synergistic stimulation in combination with Co2+ at its suboptimal concentration
Cd2+
0.002-0.005 mM, 3.5fold stimulation
Co2+
0.1-0.5 mM, 100fold increase of activity
Co2+
2500fold stimulation
Co2+
about 50% of the activity with Mn2+. In the presence of Mn2+, PrpA hydrolyzes P1,P5-bis(adenosyl)tetraphosphate mainly into AMP and ATP, whereas in the presence of Co2+ PrpA hydrolyzes P1,P5-bis(adenosyl)tetraphosphate into two molecules of ADP, reaction of EC 3.6.1.17; required for ApnA hydrolysis
Co2+
symmetrical Ap4A hydrolase is Co2+-dependent
Mg2+
weak stimulation in absence of other divalent metal ions, high synergistic stimulation in combination with Co2+ at its suboptimal concentrations
Mn2+
0.2-0.5 mM, 8fold stimulation
Mn2+
900fold stimulation
Results 1 - 10 of 12 > >>