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EC Number	Metals/Ions	Commentary	Reference
2.5.1.6	Ca2+	0.02 mM stimulates activity	685392
2.5.1.6	Co2+	-	639056
2.5.1.6	Co2+	0.02 mM stimulates activity	685392
2.5.1.6	Co2+	can replace Mg2+ with a lower relative activity, S-adenosylmethionine synthetase B	639048
2.5.1.6	Co2+	can replace Mg2+ with lower relative activity	639048
2.5.1.6	Co2+	for maximal activation the cation concentration must be at least equal to ATP concentration	639045
2.5.1.6	Co2+	high activity in the presence of 20 mM Zn2+	738285
2.5.1.6	Cs+	-	639056
2.5.1.6	K+	-	639040, 639056, 673793, 674742, 675169, 675572, 676135, 676290, 676530
2.5.1.6	K+	0.2 mM stimulates activity	685392

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Release 2023.1 (January 2023)