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Results 1 - 5 of 5
EC Number
Metals/Ions
Commentary
Reference
Fe2+
4 residues within this motif are critical for the coordination of Fe2+ and 2-oxoglutarate binding as well as functionality of this family of enzymes; acts as cofactor, 4 residues within this motif are critical for the coordination of Fe2+ and 2-oxoglutarate binding as well as functionality of this family of enzymes
Fe2+
dependent on, required for catalysis
Fe2+
non-heme
more
Ni2+ and Ca2+ cannot substitute for Fe2+, binding structure with truncated enzyme mutant. Residues His214, Asp216 and His271 play essential roles in the metal ion binding
Results 1 - 5 of 5