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EC Number
Metals/Ions
Commentary
Reference
3.5.4.4
Hg2+
-
686577
3.5.4.4
lithium ion
-
686577
3.5.4.4
Mg2+
91% inhibition
686577
3.5.4.4
Ni2+
-
686577
3.5.4.4
Zn2+
-
686577
,
699553
3.5.4.4
Mg2+
activates
686612
3.5.4.4
more
no effect on activity of Ca2+, Mg2+
697462
3.5.4.4
Zn2+
ADA contains a tightly bound Zn2+ which is required for activity, the stability of the protein is decreased significantly in the absence of Zn2+
712858
3.5.4.4
more
there are no significant changes in ADA activity in the presence of cadmium acetate, potassium dichromate, lead acetate, zinc chloride, copper sulfate, cobalt chloride, and manganese chloride
713127
3.5.4.4
Fe2+
the activity found in the enzymes expressed with added Zn(II) and added Fe(II) are 2fold higher than when expressed with Ni(II) or without additional metal
727779
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