EC Number   |
Metals/Ions |
Reference  |
|---|
   6.5.1.3 | Mg2+ |
Mg2+ or Mn2+ required |
662241 |
| 6.5.1.3 | Mn2+ |
Mg2+ or Mn2+ required |
662241 |
| 6.5.1.3 | Mg2+ |
magnesium ion interacts with the beta and gamma-phosphate groups and is almost perfectly octahedrally coordinated by six phosphate and water oxygen atoms |
662636 |
| 6.5.1.3 | Mg2+ |
activates, optimum: 5-10 mM |
662976 |
| 6.5.1.3 | Mn2+ |
activates, showing slightly higher activity than Mg2+ |
662976 |
| 6.5.1.3 | Mg2+ |
the active site contains two metal ions, consistent with the two-magnesium ion catalytic mechanism |
674568 |
| 6.5.1.3 | Mg2+ |
L1 ligase is an obligate metalloenzyme that is highly specific for Mg2+. It is selected in the presence of 60 mM MgCl2 and functions optimally in Mg2+ concentrations as high as 100 mM |
677128 |
| 6.5.1.3 | Mg2+ |
dependent on |
747437 |
| 6.5.1.3 | Mn2+ |
the enzyme prefers manganese as the metal cofactor for nick sealing |
749172 |
| 6.5.1.3 | Mg2+ |
enzyme activity is optimal at 5 mM Mg2+ |
749277 |
